Custom Search

INDEX Brain Upgrade Neurotechnology Medical Dictionary Brain Facts How 1 to 10



INDEX Brain Upgrade|Neurotechnology| Medical Dictionary|How 1 to 10

Alzheimer disease is the most common cause of dementia, responsible for 60-80% of all dementias. The prevalence is strongly linked to age, with >1% of 60-64-year-old patients being diagnosed with the condition, compared to 20-40% of those over 85-90 years of age.

Epidemiological risk factors have been identified, including:

- advanced age
- female gender
- apolipoprotein E (APOE) e4 allele carrier status
- current smoking
- a family history of dementia
- mutations of amyloid precursor protein
- Down syndrome

It should also be noted that in addition to the genetic and environmental factors above, the age of an individual's presentation will also be influenced by socio-economic factors such as:

- fewer years of formal education
- lower income
- lower occupational status
- smaller social network/family support

It is not so much that these factors are risk factors to the underlying pathology but rather that individuals with pre-morbid higher function/supports are able to compensate for early disease changes to a greater degree, and thus present later. This is supported by the fact that these high functioning individuals when they eventually present, tend to have more marked morphological changes.

Custom Search

INDEX Brain Foods Skin Care Neurotechnology Brain Facts How 1 to 10